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## StatsToDo: Squential Analaysis for Unpaired Survival Rates (Whitehead)

MacroPlot Resources
Explanations Example Javascript Program

### Calculations for Sequential Analysis for Two Unpaired Survival Rates

 Data Data is in 4 columns Col 1 = number that met with the index event (mortality) in group 1 Col 2 = number that had not met the index event (survived) in group 1 Col 3 = number that met with the index event (mortality) in group 2 Col 4 = number that had not met the index event (survived) in group 2 The number of rows are multiples of number of intervals, each set represents data from one of the sequential observations. Within each set, the rows are in order of time intervals. Each row is therefore the survival data of that interval in that set of observations.
Probability of Type I Error (α) (one tail)
Power (1 - β)
Expected Proportion survived in group 1
Expected Proportion survived in group 2
Number of time intervals
Expected Ratio of Sample Size in the 2 Groups(ratio=n1/n2)
MacroPlot Code